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Simulate workplace exposure with ECETOC TRA

Model inhalation and dermal exposure for each component in a mixture using the ECETOC TRA 3.2 method.

The ECETOC TRA 3.2 exposure simulation calculates predicted workplace exposure levels for each substance in a mixture. It compares these against occupational exposure limits (OELs) to produce risk characterisation ratios (RCRs), helping you decide whether existing controls are adequate or need strengthening.

ECETOC TRA wizard showing Step 1: Product Setup

Run an exposure simulation

Open any product from your library and navigate to the Simulate page. The wizard has five steps.

Step 1: Set up the product

Select the Physical State (liquid or solid) and enter the Dilution (%). Use 100% for undiluted products.

Step 2: Select a component

Choose which substance in the mixture to assess. Each component shows its name, CAS number, and concentration. Components missing required data (such as molecular weight) are flagged with a warning icon.

Step 3: Enter component properties

Provide or confirm the physical properties NextSDS needs for the calculation:

  • For liquids: molecular weight (g/mol) and vapour pressure (Pa)
  • For solids: dustiness level (low, medium, or high)

Optionally select an OEL country and enter exposure limits: long-term inhalation (mg/m³), long-term dermal (mg/kg/day), local dermal (µg/cm²), and short-term inhalation (mg/m³). These limits are used to calculate risk characterisation ratios in the results.

Step 4: Define the use scenario

Describe how the product is used in your workplace:

  • Process Category (PROC): select from 25 standard European process categories (PROC 1–25), ranging from closed processes to open spraying
  • Use Type: industrial or professional
  • Exposure Duration: under 15 minutes, 15 minutes to 1 hour, or over 4 hours
  • Ventilation: outdoors, indoor with no ventilation, good ventilation, or enhanced (mechanical) ventilation
  • Local Exhaust Ventilation: whether LEV is used for inhalation and/or dermal protection
  • PPE: respiratory protection efficiency (none, 90%, or 95%) and glove efficiency (none, 80%, 90%, or 95%)

Select Calculate Exposure to run the simulation.

Step 5: Review results

The results table shows predicted exposure values and RCRs for each substance:

ColumnWhat it shows
8-Hour ExposurePredicted inhalation (mg/m³), dermal (mg/kg/day), and local dermal (µg/cm²) values
Short-term ExposurePredicted inhalation and local dermal values for peak exposures
RCRRisk characterisation ratio: predicted exposure divided by the OEL

RCR values are colour-coded:

  • Green (below 0.8): exposure is well within the limit
  • Yellow (0.8–1.0): exposure is close to the limit
  • Red (above 1.0): exposure exceeds the limit; additional controls are needed

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